β‐Cyclodextrin–Glycerol Dimers: Synthesis and NMR Conformational Analysis

• DOI: 10.1002/ejoc.201201716
• Publication Date: 2013-03-14T08:24:18Z
• Authors: Vanessa Legros; Cécile Vanhaverbeke; Florence Souard; Christophe Len; Jérôme Désiré
• Keywords: Rotaxane

Abstract The synthesis of new β‐cyclodextrin dimers linked through their primary faces by different glycerol‐like moieties click chemistry is described. unusual behaviour these cyclodextrin–glycerol in aqueous solution has been studied NMR spectroscopy. We show that, depending on the length linking arm between two cyclodextrins, could adopt very conformations water: symmetrical or pseudo[1]rotaxane‐like structures one D ‐glucopyranose unit tumbling β‐cyclodextrin.