Coordinating Chiral Ionic Liquids: Design, Synthesis, and Application in Asymmetric Transfer Hydrogenation under Aqueous Conditions

• DOI: 10.1002/ejoc.201403555
• Publication Date: 2015-02-20T10:28:03Z
• Authors: Maria Vasiloiu; Peter Gaertner; Ronald Zirbs; Katharina Bica
• Keywords: Transfer hydrogenation; Chirality

Hydrophilic coordinating chiral ionic liquids with an amino alcohol substructure were developed and efficiently applied to the asymmetric reduction of ketones. Their careful design adaptability desired reaction conditions allow for these be used as sole source chirality in a ruthenium-catalyzed transfer hydrogenation aromatic When this system, afforded excellent yields high enantioselectivities.