Longitudinal microstructural alterations surrounding subcortical ischemic stroke lesions detected by free‐water imaging

• DOI: 10.1002/hbm.26722
• Publication Date: 2024-05-23T13:43:29Z
• Authors: Felix L. Nägele; Marvin Petersen; Carola Mayer; Marlene Bönstrup; Robert Schulz; Christian Gerloff; Götz Thomalla; Bastian Cheng
• Keywords: Stroke

In this study we explore the spatio-temporal trajectory and clinical relevance of microstructural white matter changes within beyond subcortical stroke lesions detected by free-water imaging. Twenty-seven patients with infarct mean age 66.73 (SD 11.57) median initial NIHSS score 4 (IQR 3-7) received diffusion MRI 3-5 days, 1 month, 3 months, 12 months after symptom-onset. Extracellular fractional anisotropy tissue (FA