Parotid gland stem cells: Mini yet mighty

• DOI: 10.1002/hed.26556
• Publication Date: 2020-11-27T08:41:13Z
• Authors: Sezin Yuce Sari; Melek Tugce Yilmaz; Aysenur Elmali; Fazli Yagiz Yedekci; Deniz Yuce; Gokhan Ozyigit; Mustafa Cengiz; Gozde Yazici
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Head and Neck Neoplasms; Stem Cells; Humans; Parotid Gland; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Xerostomia; Retrospective Studies; 3. Good health

Abstract Background Our aim was to evaluate the correlation between radiation doses parotid gland (PG) stem cells and xerostomia. Methods Patients diagnosed with head neck cancer (HNC) were retrospectively evaluated, xerostomia inventory (XI) applied these patients. PG delineated on treatment planning CT, mean calculated. Results The total test score bilateral PGs significantly correlated ( r = .34, P .001), cell niches .32, .002). Conclusions In this study, we found that dose can predict dry mouth as much PG.