Feasibility of ipsilateral elective neck irradiation of levels Ib and II without level III in patients with node‐negative sinonasal squamous cell carcinoma

• DOI: 10.1002/hed.27278
• Publication Date: 2022-12-19T11:48:19Z
• Authors: Qian Liu; Lixin Lun; Meng Sun; Zekun Wang; Xiaodong Huang; Xuesong Chen; Jingbo Wang; Jianghu Zhang; Yuan Qu; Kai Wang; Runye Wu; Ye Zhang; Jianping Xiao; Junlin Yi; Jingwei Luo
• Keywords: Squamous Cell Carcinoma of Head and Neck; Disease-Free Survival; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Carcinoma, Squamous Cell; Humans; Feasibility Studies; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Retrospective Studies; Neoplasm Staging

The necessity of level III irradiation in patients with node-negative advanced sinonasal squamous cell carcinoma (SNSCC) is unclear.Seventy-eight SNSCC were included. Survival rates estimated and compared between treatment groups.Twenty-five received ipsilateral levels Ib II (group 1) 53 plus 2). median follow-up time was 75.56 months. Five-year survival (regional relapse-free survival, overall local distant metastasis-free survival) similar groups 1 2 (all p > 0.05). Irradiation doses to the thyroid larynx significantly lower group than 2.Ipsilateral neck provides regional control results as these III, normal tissue, SNSCC.