Accuracy and disagreement of computed tomography and magnetic resonance imaging for the diagnosis of small hepatocellular carcinoma and dysplastic nodules: Role of biopsy

• DOI: 10.1002/hep.24746
• Publication Date: 2011-10-17T15:46:05Z
• Authors: Thomas Sersté; Vincent Barrau; Violaine Ozenne; Marie-Pierre Vull...; Pierre Bedossa; Olivier Farges; Dominique-Charles...; Valérie Vilgrain; Valérie Paradis; Françoise Degos
• Keywords: Nodule (geology)

Liver macronodules, ranging from benign to low-grade or high-grade dysplastic nodules (LGDNs/HGDNs) and hepatocellular carcinoma (HCC), may develop during chronic liver diseases (CLDs). Current guidelines were recently updated the noninvasive criteria for diagnosis of small HCC are based on a single typical radiological pattern nonconclusive coincidental findings with two techniques. This study aimed assess accuracy disagreements multiphasic examinations (DNs) role biopsy. Seventy-four consecutive patients CLD ultrasound-detected 1-2-cm underwent, within 1 month, computed tomography (CT), magnetic resonance imaging (MRI), biopsy nodule. Median age was 60 years; 33 (45%) had hepatitis C virus, 20 (27%) B 13 (18%) no cirrhosis. Biopsy revealed 47 HCCs, 6 HGDNs, LGDNs, cholangiocarcinoma, epithelioid hemangioendothelioma. There tumors in other 18 patients. All (31 31; 100%) who conclusive (i.e., arterial enhancement washout) both HGDN (sensitivity, 57%; specificity, 100%). (51 51; at least one 96%; disagreement regarding between CT MRI 21 74 (28%) washout 23 (31%). In these 44 patients, provided an initial accurate diagnosis. Conclusion : The can be obtained if found dynamic examination. These frequently discordant MRI, supporting place HCCs.