Spontaneous Regression of Hepatocellular Carcinoma: When the Immune System Stands Up to Cancer
Male
0303 health sciences
Carcinoma, Hepatocellular
Liver Neoplasms
Receptors, IgG
Immunity
Middle Aged
GPI-Linked Proteins
Lymphocyte Activation
Monocytes
3. Good health
Killer Cells, Natural
Pneumococcal Vaccines
03 medical and health sciences
Neoplasm Regression, Spontaneous
Asymptomatic Diseases
Humans
Female
Chemokine CCL4
Aged
T-Lymphocytes, Cytotoxic
DOI:
10.1002/hep.31489
Publication Date:
2020-08-02T20:08:57Z
AUTHORS (5)
ABSTRACT
Spontaneous regression of cancer is rare and has been observed mostly in immunogenic cancers like melanoma. A few cases of spontaneous regression of hepatocellular carcinoma (HCC) have been reported, but the mechanisms of regression have not been elucidated. Here, we report a patient with advanced HCC who experienced spontaneous regression of her tumor and present evidence for a putative immune-mediated mechanism for tumor regression.
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