Spontaneous Regression of Hepatocellular Carcinoma: When the Immune System Stands Up to Cancer

Male 0303 health sciences Carcinoma, Hepatocellular Liver Neoplasms Receptors, IgG Immunity Middle Aged GPI-Linked Proteins Lymphocyte Activation Monocytes 3. Good health Killer Cells, Natural Pneumococcal Vaccines 03 medical and health sciences Neoplasm Regression, Spontaneous Asymptomatic Diseases Humans Female Chemokine CCL4 Aged T-Lymphocytes, Cytotoxic
DOI: 10.1002/hep.31489 Publication Date: 2020-08-02T20:08:57Z
ABSTRACT
Spontaneous regression of cancer is rare and has been observed mostly in immunogenic cancers like melanoma. A few cases of spontaneous regression of hepatocellular carcinoma (HCC) have been reported, but the mechanisms of regression have not been elucidated. Here, we report a patient with advanced HCC who experienced spontaneous regression of her tumor and present evidence for a putative immune-mediated mechanism for tumor regression.
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