Hematologic malignancies and COVID‐19 infection: A monocenter retrospective study

• DOI: 10.1002/hsr2.638
• Publication Date: 2022-05-23T05:54:18Z
• Authors: Hamed Azhdari Teh...; Soodeh Ramezaninejad; Masoud Mardani; Shervin Shokouhi; Maryam Darnahal; Atousa Hakamifard
• Keywords: Case fatality rate; Hematologic malignancy; Hematologic disease

Hematologic malignancies are risk factors for severe COVID-19 infection. Identification of correlated with mortality in these groups patients is important the assessment strategy. We studied characteristics hematologic and then analyzed predictors mortality.Eligible analysis were hospitalized confirmed infection observed between January 2020 March 2021. Patients categorized based on type malignancy phase treatment.A total 194 infected included. The median age was 44 (15-81) years; 135 them males 59 females. Acute myeloid leukemia most frequent cancer (43.8%). A 119 had 61 admitted to intensive care unit. 92 deaths occurred all cases an overall case-fatality rate 47%. Male gender, preinduction induction treatment, admission, low levels oxygen saturation, Rhesus (RH) factor positivity, higher fibrinogen level mortality.This study focuses epidemiology, factors, outcomes, among malignancies. at high mortality.