Second primary neoplasms in 633,964 cancer patients in Sweden, 1958-1996

• DOI: 10.1002/ijc.1317
• Publication Date: 2002-10-28T13:56:28Z
• Authors: Chuanhui Dong; Kari Hemminki
• Keywords: Male; Sweden; Databases, Factual; Neoplasms, Second Primary; Risk Assessment; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Neoplasms; Humans; Female; Follow-Up Studies

The Swedish Family-Cancer Database was used to analyze concordant (same site) and discordant (different second primary neoplasms in 633,964 cancer patients diagnosed from 1958 1996. Cases of malignant were extracted the if diagnosis date first differed by at least 1 month. expected numbers cancers obtained applying site-, sex-, age-, period-, residence- socioeconomic level-specific rates corresponding population appropriate person-years risk. standardized incidence ratio (SIRs) a taken be observed cancers. Of all cancers, 8.5% subsequent (8.4% for males 8.7% females). SIRs both elevated with upper aerodigestive tract, colon, nose, breast, other female genitals, testis, kidney, urinary, bladder, skin, nervous system, endocrine, bone, connective tissue, melanoma, lymphoma leukemia. risks some sites, such as squamous cell bone tissue sexes, breast tract leukemia females, very high (>10). At less than 2 but significantly increased after gastric prostatic cancer. Compared general population, modestly risk new many calling attention treatment, management prevention. © 2001 Wiley-Liss, Inc.