The evolving epidemic of breast cancer in sub‐Saharan Africa: Results from the African Cancer Registry Network

• DOI: 10.1002/ijc.33014
• Publication Date: 2020-04-19T09:54:28Z
• Authors: Walburga Yvonne J...; Elima Jedy‐Agba; Anne Korir; Olufemi Ogunbiyi; Charles P. Dzamalala; Eric Chokunonga; Henry Wabinga; Shyam Manraj; Anne Finesse; Nontuthuzelo Somd...; Biying Liu; Paul McGale; Ahmedin Jemal; Freddie Bray; Donald Maxwell Pa...
• Keywords: Cumulative incidence

Breast cancer (BC) is the leading cause of in sub-Saharan Africa (SSA) with rapidly increasing incidence rates reported Uganda and Zimbabwe. However, magnitude these rising trends premenopausal postmenopausal women unknown most African countries. We used data from Cancer Registry Network on incident breast cancers 11 population-based registries 10 countries representing each four SSA regions. explored changes among before after age 50 by calendar period and, where possible, generational effects this unique cohort. Temporal revealed all during study period, except Nairobi stabilised 2010 to 2014 2003 (APC = 8.5 95%, CI: 3.0-14.2). The cumulative risk varied between within regions, highest risks observed Nairobi-Kenya, Mauritius Seychelles. There were similar or more aged 50+ compared <50 years Gambia. Birth cohort analyses increases successive generations 45 over Harare-Zimbabwe Kampala-Uganda. In conclusion, BC many parts Africa; however, differs. These results highlight need for urgent actions across continuum in-depth factor studies provision adequate therapy as well necessity supporting maintenance good quality registration Africa.