Prediction of lymph node metastasis in oral tongue squamous cell carcinoma using the neutrophil‐to‐lymphocyte ratio and platelet‐to‐neutrophil ratio

• DOI: 10.1002/jcla.23684
• Publication Date: 2021-05-04T07:19:43Z
• Authors: Bo Wang; Junwen Liu; Zhengrong Zhong
• Keywords: Venous blood

Lymph node metastasis in a variety of tumors is associated with systemic inflammatory markers. However, this association has not been reported oral tongue squamous cell carcinoma (OTSCC). This study aimed to investigate how the preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-neutrophil (PNR) OTSCC patients correlated occurrence lymph metastasis.The data 73 primary who underwent surgical resection were retrospectively analyzed. Patients other malignant tumors, had received radiotherapy or chemotherapy before surgery, active inflammation excluded. The enrolled divided into groups N0 (no early-stage metastasis) N1 (early-stage metastasis). Venous blood samples collected surgery at third week after subjected complete counting analyzer. Eighty-seven healthy people included as control group. In addition, NLR PNR compared those controls, postoperative group .The was significantly higher than controls (p < 0.05). area under receiver operating characteristic curve 0.595. Further comparison PLR between showed that when ≤1.622, probability 73.3%, >60.889, 86.7%. re-examination 3 weeks postoperatively, different groups.The certain reference value for diagnosis OTSCC. can be used predict histopathologically confirmed