Design, Synthesis, and Biological Screening of Novel Anthranilic Diamides

• DOI: 10.1002/jhet.2351
• Publication Date: 2015-06-23T05:53:13Z
• Authors: Xuewen Hua; Wutao Mao; Zhijin Fan; Xiaotian Ji; Fengyun Li; Guangning Zong; Haibin Song; Kalinina Tatiana; Yury Yu. Morzherin; Nataliya P. Belskaya; Vasiliy A. Bakulev
• Keywords: 0301 basic medicine; 03 medical and health sciences

Three series of new anthranilic diamide derivatives containing sulfide, N‐cyanomethylsulfilimine, and N‐cyanomethylsulfoximine groups were designed and synthesized by combining the active substructures of anthranilic diamides and sulfoxaflor. The structures of all newly synthesized compounds were confirmed by IR and 1H/13C‐NMR, and some of them were confirmed by elemental analysis or HRMS too. The synthesized compounds were screened for their insecticidal and fungicidal activities. Bioasssay results indicated that some of the synthesized compounds possessed certain degrees of insecticidal activity against Mythimna separata. However, some compounds exhibited good fungicidal activity against Sclerotinia sclerotiorum.