Characterizing the electrospray ionization mass spectral fragmentation pattern of indole derivatives synthesized from 2‐keto glycosides

• DOI: 10.1002/jms.814
• Publication Date: 2005-02-22T10:46:32Z
• Authors: Shuxia Cao; Hongmin Liu; Wen Xu; Xincheng Liao; Yufen Zhao
• Keywords: Fragmentation; Collision-induced dissociation

Abstract Four indole derivatives synthesized from 2‐keto glycosides were analyzed by electrospray ionization tandem mass spectrometry (ESI‐MS n ) with low‐energy collision‐induced dissociation to establish a general structural elucidation of derivatives. Their fragmentation pathways are proposed on the basis MS studies and deuterium‐labeled experiments. Indole undergo complicated gas‐phase rearrangements in addition simple bond cleavages. A rearrangement, which involves contraction six‐membered ring, was observed mechanism proposed. The observations may have some potential applications interpretation spectra Copyright © 2005 John Wiley & Sons, Ltd.