Evaluation of microbiome in primary and permanent dentition in grade C periodontitis in young individuals

• DOI: 10.1002/jper.23-0504
• Publication Date: 2024-03-13T07:29:50Z
• Authors: Sungeun Stephanie...; Jussara G. Fernandes; Lu Li; Hong Huang; Ikramuddin Aukhil; Peter Harrison; Patricia I. Diaz; Luciana M. Shaddox
• Keywords: Permanent dentition

Abstract Background The aim of the present study was to evaluate subgingival microbiome in patients with grade C molar‐incisor pattern periodontitis (C‐MIP) affecting primary or permanent dentitions. Methods DNA isolated from biofilm samples diseased and healthy sites 45 C‐MIP subjected phylogenetic microarray analysis. were compared between children affected those Within‐subject differences C‐MIP‐affected dentition‐matched also evaluated. Results subjects dentition showed partially overlapping but distinct microbial communities ( p < 0.05). Differences due increased levels certain species genera Capnocytophaga Leptotrichia , while higher prevalence Filifactor alocis . Aggregatibacter actinomycetemcomitans Aa ) among seen high both sites. Moreover, when same subject 0.01). Conclusions Primary teeth a dysbiotic microbiome, showing profile dentition. However, enriched sites, confirming that this microorganism is implicated