SPNing our wheels—Pancreatic solid pseudopapillary neoplasm as an extraluminal etiology of persistent duodenal ulceration

• DOI: 10.1002/jpr3.70003
• Publication Date: 2025-03-11T13:47:56Z
• Authors: Kanak V. Kennedy; Jibraan A. Fawad; Y. Dana Neugut; Doris Valenzuela‐...; Alexander Coe; Tricia R. Bhatti; Michael Acord; Michael D. Manfredi; Petar Mamula; Kathleen M. Loomes; Jefferson N. Brow...

AbstractPediatric upper gastrointestinal (GI) bleeding secondary to duodenal ulceration is a potentially serious and life‐threatening condition with a broad differential diagnosis. We present a pediatric case of a pancreatic head solid pseudopapillary neoplasm (SPN) presenting with duodenal ulceration and recurrent upper GI bleeding. This case highlights pancreatic SPNs as a rare extrinsic cause of duodenal ulceration. Recurrence and progression in size and extent of a duodenal ulceration in the absence of other inciting factors should raise suspicion for an extraluminal etiology.