Impact of preoperative transcatheter rectal arterial chemoembolization with concurrent chemoradiotherapy on surgery and prognosis of patients with locally advanced rectal cancer

• DOI: 10.1002/jso.26673
• Publication Date: 2021-09-12T17:34:53Z
• Authors: Wenjun Meng; Bo Yang; Bin Huang; Chuan Chen; Jianwu Zhu; Dan Jian; Li Zhong; Dong Wang; Chunxue Li; Lian Bai
• Keywords: Chemoradiotherapy; Distant metastasis

Abstract Background and Objectives To analyze evaluate the impact of preoperative transcatheter rectal arterial chemoembolization (TRACE) with concurrent chemoradiotherapy on surgery prognosis locally advanced cancer (LARC). Methods A total 118 patients LARC were enrolled in this nonrandomized prospective study. They assigned into experimental group receiving TRACE (TRACE‐CRT group, N = 60) control only neoadjuvant (CRT 58). All underwent after their treatments. Results successfully completed surgical operation. No significant differences found sphincter preservation rate R0 resection between TRACE‐CRT CRT ( p > 0.05). two groups terms perioperative indicators postoperative complications except mean operation time (165.8 vs. 196.6 min, < 0.001). Local recurrence occurred 8 5 patients, respectively Distant metastasis 11 Conclusions Adding standard treatment for did not increase complications. In addition, it has potential advantage preventing distant metastasis. It is worthy further application promotion clinical practice.