Temporal Bone Osteoradionecrosis: An 18‐year, Single‐Institution Experience

• DOI: 10.1002/lary.29758
• Publication Date: 2021-07-20T11:32:23Z
• Authors: Benjamin D. Lovin; Mike Hernandez; Hunter Elms; Jonathan S. Choi; Nathan R. Lindquist; Amy C. Moreno; Marc‐Elie Nader; Paul W. Gidley
• Keywords: Osteoradionecrosis

Objectives/Hypothesis To report the largest single‐institution review of temporal bone osteoradionecrosis (TBORN), and characterize disease's natural history, prognostic factors, management, outcomes. Study Design Retrospective chart review. Methods was conducted to identify patients with TBORN. Pertinent data were extracted. Descriptive statistics used summarize patient, tumor, treatment characteristics. Multivariable analyses explore associations between these characteristics time TBORN diagnosis risk developing diffuse disease. Results identified in 145 bones from 128 patients. Mean age at 62 years, mean after radiotherapy 10 years. Age greater than 50 years associated earlier diagnosis. According Ramsden criteria, 76% TBs had localized 24% disease initial diagnosis; 37% last follow‐up. On multivariable analysis, diabetes, three‐dimensional conformal (3D‐CRT), periauricular skin malignancy significant factors for Localized successfully managed conservative measures, whereas surgery often necessary When spread outside mastoid or infratemporal fossa, measures always unsuccessful. Conclusions occurs older While is less common disease, it more frequently history 3D‐CRT, malignancies. Conservative management appropriate while The helped propose a staging system guidelines which may improve patient stratification management. Level Evidence 4 Laryngoscope , 131:2578–2585, 2021