Experimental application of pulsed Ho:YAG laser‐induced liquid jet as a novel rigid neuroendoscopic dissection device

• DOI: 10.1002/lsm.20021
• Publication Date: 2004-03-10T08:01:58Z
• Authors: Tomohiro Ohki; Atsuhiro Nakagawa; Takayuki Hirano; Tokitada Hashimoto; Viren Menezes; Hidefumi Jokura; Hiroshi Uenohara; Yasuhiko Sato; Tsutomu Saito; Reizo Shirane; Teiji Tominaga; Kazuyoshi Takayama
• Keywords: Holmium; Pulse duration

Abstract Background and Objectives Although water jet technology has been considered as a feasible neuroendoscopic dissection methodology because of its ability to perform selective tissue without thermal damage, problems associated with continuous use the ensuing fountain‐effect—with catapulting tissue—could make jets unsuitable for endoscopic use, in terms safety ease handling. Therefore, authors experimented minimization usage during application pulsed holmium:yttrium‐aluminum‐garnet (Ho:YAG) laser‐induced liquid (LILJ), while assuring quality controllability conventional device. We have developed LILJ generator rigid neuroendoscope, discerned mechanical behavior, evaluated using cadaveric rabbit ventricular wall. Study Design/Materials Methods The is incorporated into tip stainless steel tube (length: 22 cm; internal diameter: 1.0 mm; external 1.4 mm), so that device can be inserted commercial, neuroendoscope. Briefly, generated by irradiating an internally supplied column within Ho:YAG laser (wave length: 2.1 μm, pulse duration time: 350 microseconds) then ejected through metal nozzle (internal 100 μm). energy conveyed optical quartz fiber (core 400 μm), cold (5°C) at rate 40 ml/hour. relationship between (range: 40–433 mJ/pulse), standoff distance (defined end; range: 10–30 velocity, shape, pressure, average volume were analyzed means high‐speed camera, PVDF needle hydrophone, digital scale. plane, preservation blood vessels, penetration depth five fresh walls, under vision. Results Jet velocity (7.0–19.6 m/second) pressure (0.07–0.28 MPa) could controlled varying energy, which determined wall (0.07–1.30 mm/shot). latter cut desirable shapes—without effects—under clear single confined 0.42–1.52 μl/shot, there was no accompanying generation shock waves. Histological specimens revealed sharp plane demonstrated vessels diameter over μm preserved, damage. Conclusions present system holds promise safe reliable deployment Lasers Surg. Med. 34:227–234, 2004. © 2004 Wiley‐Liss, Inc.