Spatially Controlled Self‐Assembly of Supramolecular Hydrogels Enabled by Light‐Triggered Catalysis

• DOI: 10.1002/marc.202401156
• Publication Date: 2025-02-10T03:23:30Z
• Authors: Jiahao Zhang; Kaiyu Jin; Yichen Xiao; Yifei Feng; Da Lu; Mai Chen; Mengran Sun; Dengyu Wang; Cheng Jin; Zhiling Li; Yiming Wang
• Keywords: Hydrazone; Supramolecular assembly

Spatial control over supramolecular self-assembly prevails in living system, yet remains difficult to replicate synthetic scenarios. Here, on the basis of a hydrazone formation-mediated hydrogelation access patterning hydrogels is demonstrated via light-triggered catalysis strategy. A photoacid generator that can produce protons aqueous solutions upon irradiation employed. The generated lead drop pH around three units (initial 7.0), effectively accelerating formation and gelators. Because catalysis, samples presence show lower critical gelation concentration, higher stiffness, denser networks. Importantly, by performing selective using differently shaped masks, various spatially resolved following shapes masks are fabricated. concept realize spatial provides an alternative approach toward bottom-up fabrication structured soft materials for applications such as tissue engineering, single cell manipulation, biosensing.