Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease

• DOI: 10.1002/mds.10265
• Publication Date: 2002-12-04T14:20:29Z
• Authors: Luigi Michele Romito; Michele Raja; Antonio Daniele; Maria Fiorella Co...; Anna Rita Bentivo...; Annalisa Barbier; Massimo Scerrati; Alberto Albanese
• Keywords: Adult; Male; Neurologic Examination; Motivation; Bipolar Disorder; Sexual Behavior; Electric Stimulation Therapy; Parkinson Disease; Middle Aged; Electrodes, Implanted; 3. Good health; 03 medical and health sciences; Postoperative Complications; 0302 clinical medicine; Subthalamic Nucleus; Humans; Female; Arousal; Dominance, Cerebral; Follow-Up Studies

AbstractAmong 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously. © 2002 Movement Disorder Society