Simultaneous brain and neck time‐of‐flight MRA using spiral multiband with localized quadratic encoding

• DOI: 10.1002/mrm.30098
• Publication Date: 2024-04-05T04:18:54Z
• Authors: Xi Peng; Dinghui Wang; Daniel Borup; Guruprasad Krishn...; James G. Pipe
• Keywords: SIGNAL (programming language); Magnetic resonance angiography; Flip angle

Abstract Purpose To develop a method that achieves simultaneous brain and neck time‐of‐flight (ToF) magnetic resonance angiography (MRA) within feasible scan timeframes. Methods Localized quadratic (LQ) encoding is efficient for both signal‐to‐noise ratio (SNR) in‐flow enhancement. We proposed spiral multiband LQ to enable intracranial carotid ToF‐MRA single scan. address the venous signal contamination becomes challenge with (MB) ToF, tilt‐optimized non‐saturated excitation (TONE) partial‐Fourier slice selection (PFSS) were further introduced in framework mitigate improve artery contrast. A sequential MB reconstruction pipeline was employed obtain brain‐and‐neck image volumes. Results The able achieve 2:50‐min complementarily boosted SNR‐efficiency by acquisitions allows increased spatial coverage without increase time or noticeable compromise SNR. incorporation of TONE PFSS effectively alleviated improved small vessel sensitivity. Selection parameters such as factor flip angle reflected trade‐off among SNR, blood contrast, suppression. Conclusions novel approach fast minimized corruption. has shown promise MRA applications where large necessary.