Symptomatic preterm infants suffer from lung function deficits, regardless of bronchopulmonary dysplasia

• DOI: 10.1002/ppul.26144
• Publication Date: 2022-09-13T08:08:55Z
• Authors: Jana Tuková; Václav Koucký; Daniela Marková; Petr Koťátko; Marie Hladíková; Jan Šulc
• Keywords: Bronchopulmonary Dysplasia; Univariate analysis

The long-term respiratory consequences for children with bronchopulmonary dysplasia (BPD) are well known. However, there is little emphasis on monitoring preterm infants without BPD. Few studies have explored the lung function status of symptoms chronic disease prematurity (CLD).To evaluate functional deficits in CLD, and to assess perinatal determinants diminished function.In our cross-sectional study, 132 symptomatic CLD underwent infant pulmonary testing (iPFT) at a median post-term age 0.9 years. iPFT included bodypletysmography, compliance measurement, tidal breath analysis, rapid thoracoabdominal compression. relationships between respective z scores parameters characteristics, postnatal treatment, BPD were investigated.Seventy-three patients (55.3%) born before 28th week gestation, 92 (69.7%) met criteria. Functional detected 85.8%. obstructive ventilatory pattern was more prevalent than restrictive (36.3 vs. 12.4%, p < 0.001). Infants restriction had lower birth weight (BW) required longer duration oxygenotherapy. In univariate model, correlated invasive mechanical ventilation, gestational week, BW. general linear not an additional determinant results.IPFT may reveal significant even current factors be important itself.