A potential link between aromatics‐induced oviposition repellency behaviors and specific odorant receptor of Aedes albopictus

• DOI: 10.1002/ps.8064
• Publication Date: 2024-03-08T23:05:44Z
• Authors: Ru Yan; Peitong Chen; Zhanyi Xu; Jiali Qian; Guonian Zhu; Yongfeng Jin; Bosheng Chen; Mengli Chen
• Keywords: Aedes albopictus; Semiochemical; Odorant-binding protein; Kairomone

Abstract BACKGROUND The Asian tiger mosquito, Aedes albopictus , is a competent vector for the spread of several viral arboviruses including dengue, chikungunya, and Zika. Several vital mosquito behaviors linked to survival reproduction are primarily dependent on sophisticated olfactory system semiochemical perception. However, limited number studies has hampered our understanding relationship between A. acute complex chemical world. RESULTS Here, we performed qRT‐PCR assay antennae from differing sex, age physiological states, found that AalbOr10 was enriched in blood‐fed female mosquitoes. We then undertook single sensillum recording de‐orphan using panel physiologically behaviorally relevant odorants Drosophila ‘empty neuron’ system. results indicated activated by seven aromatic compounds, all which egg‐laying Furthermore, post‐RNA interference oviposition assay, reducing transcript level affected repellent activity mediated 2‐ethylphenol at low concentrations (10 −4 vol/vol). Computational modeling molecular docking suggested hydrogen bonds Y68 Y150 interaction with AalbOr10. CONCLUSION reveal potential link aromatics‐induced repellency specific odorant receptor . Our findings provide foundation identifying active semiochemicals monitoring or controlling populations. © 2024 Society Chemical Industry.