Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin

• DOI: 10.1002/ptr.2726
• Publication Date: 2009-01-23T15:50:21Z
• Authors: Atiya Fatima; Vivek K. Gupta; Suaib Luqman; Arvind S. Negi; J. K. Kumar; Karuna Shanker; Dharmendra Saikia; Suchita Srivastava; M. P. Darokar; Suman P.S. Khanuja
• Keywords: Glycyrrhiza

Abstract Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity drug resistant mutants Candida albicans at a minimum inhibitory concentration 31.25–250 µg/mL. Although the compound reported earlier , but this is first report its mutants. Copyright © 2009 John Wiley & Sons, Ltd.