Photothermal‐enhanced in situ supramolecular hydrogel promotes bacteria‐infected wound healing in diabetes

• DOI: 10.1002/smmd.20230047
• Publication Date: 2024-02-23T12:00:29Z
• Authors: Chen Zheng; Xuan Wu; Ming Liu; Yulong Lan; Qian Liu; Erya Cai; Zhiyong Liao; Jianliang Shen
• Keywords: antibacterial; photothermal therapy; Medical technology; injectable hydrogel; 02 engineering and technology; in situ hydrogel; R855-855.5; 0210 nano-technology; diabetic wound healing; Research Article

Bacterial infection can impede the healing of chronic wounds, particularly diabetic wounds. The high-sugar environment wounds creates a favorable condition for bacterial growth, posing challenge to wound healing. In clinical treatment, irregular shape and poor mechanical properties traditional gel adjuvants make them susceptible shear compression, leading morphological changes fractures, difficult adapt Traditional are prepared in advance, while situ is formed at site administration after drug delivery liquid state, which better fit wound. Therefore, this study developed an HA/GCA/Fe