Clinically oriented three‐step strategy for assessment of adnexal pathology

• DOI: 10.1002/uog.11177
• Publication Date: 2012-04-18T08:23:07Z
• Authors: L. Ameye; D. Timmerman; L. Valentin; D. Paladini; J. Zhang; C. Van Holsbeke; A. A. Lissoni; L. Savelli; J. Veldman; A. C. Testa; F. Amant; S. Van Huffel; T. Bourne
• Keywords: Vascularity

To determine the diagnostic performance of ultrasound-based simple rules, risk malignancy index (RMI), two logistic regression models (LR1 and LR2) real-time subjective assessment by experienced ultrasound examiners following exclusion masses likely to be judged as easy 'instant' diagnose an examiner, develop a new strategy for adnexal pathology based on this.3511 patients with at least one persistent mass preoperatively underwent transvaginal ultrasonography assess tumor morphology vascularity. They were included in consecutive prospective studies International Ovarian Tumor Analysis (IOTA) group: Phase 1 (1999-2005), development rules LR1 LR2, 2, validation study (2005-2007).Almost half cases (43%) identified basis descriptors applied database. more difficult 'non-instant' masses, we used only 2 data (n = 1036). The sensitivity LR2 was 88%, RMI it 41% 87%. specificity 67%, 90% 86%. yielded conclusive result almost 2/3 where they resulted similar those examiners: 89 vs 89% (P 0.76), 91 91% 0.65). When three-step diagnoses Step 1, examiner remaining 3, obtained 92% compared 0.03) 93% 0.44) when using experts all tumors.A variables contained IOTA database obtains results that are good expert.