OP29.07: Non‐invasive in utero measurements of placental oxygen transport using MRI

• DOI: 10.1002/uog.16443
• Publication Date: 2023-09-12T23:42:13Z
• Authors: B.S. Saini; M. Zhu; S. Portnoy; P. Porayette; J. Lim; A. Duan; J.G. Sled; R. Wald; R. Windrim; C. Macgowan; J.C. Kingdom; M. Seed
• Keywords: Oxygen transport; Venous blood

To investigate the use of MRI to assess placental function in terms placental-fetal oxygen (O2) transport utero. Eight women with normal pregnancies were scanned using a 1.5 T Siemens system. measure O2 transport, blood flow (Q) and content (C) measured vessels supplying (uterine arteries fetal descending aorta) draining (uterine, ovarian umbilical veins) placenta. Phase contrast was used Q. Vascular T1 T2 relaxometry saturation hematocrit derive C. The delivery (Do2) return (Ro2) calculated as C*Q. Oxygen consumption (Vo2) arterio-venous difference C supplied drained from an organ multiplying it by All measures indexed weight, which 3D acquisition uterus. mean placental-Vo2 4.1 ml/min/kg, accounted for 33.9% total placental-fetal-Vo2. fetal-Vo2 8.0 ml/min/kg placental-to ratio 0.53 (see table 1).