Reliability of the lung‐to‐head ratio in predicting outcome and neonatal ventilation parameters in fetuses with congenital diaphragmatic hernia

• DOI: 10.1002/uog.1837
• Publication Date: 2005-01-19T15:47:17Z
• Authors: K. S. Heling; R. R. Wauer; H. Hammer; R. Bollmann; R. Chaoui
• Keywords: Single Center

Abstract Objectives The ratio of the lung area (on contralateral side hernia) to head circumference, lung‐to‐head (LHR), has been proposed as a reliable tool in assessment prognosis congenital diaphragmatic hernia (CDH). An LHR < 0.6 associated with poor outcome whereas one > 1.4 survival. We aimed analyze role predicting fetal and ventilation parameters cases isolated CDH our center. Methods During 40‐month study period, 22 fetuses an were delivered alive under optimized conditions at perinatal was measured time diagnosis (median, 27 weeks' gestation). In addition survival, postnatal including pCO 2 , pO inspiratory O partial pressure, pressure oxygenation index determined, occurrence pulmonary hypertension. Results overall survival rate 59%. not able predict reliably. There no correlation between liver herniation, outcome. prenatally determined size reflected did show any significant association individual parameters. Eleven 17 infants examined had signs hypertension this condition. Conclusion Our cannot support optimistic results reported by other groups on use predictor CDH. LHR, reflection size, correlates neither patterns nor various Copyright © 2005 ISUOG. Published John Wiley & Sons, Ltd.