Prenatal prediction of survival in isolated left‐sided diaphragmatic hernia

• DOI: 10.1002/uog.2688
• Publication Date: 2005-12-22T14:16:43Z
• Authors: J. Jani; R. L. Keller; A. Benachi; K. H. Nicolaides; R. Favre; E. Gratacos; J. Laudy; V. Eisenberg; A. Eggink; P. Vaast; J. Deprest
• Keywords: Thorax (insect anatomy)

Abstract Objective To investigate the potential value of antenatally determined intrathoracic herniation liver and ratio fetal lung area to head circumference (LHR) in prediction postnatal survival isolated, left‐sided congenital diaphragmatic hernia (CDH). Methods In this multicenter study, we searched antenatal‐CDH‐Registry for fetuses with isolated CDH that were liveborn after 30 weeks gestation followed up postnatally at least 3 months discharge from hospital. The patients subdivided into those without subgroups according LHR had been measured between 22 + 0 28 gestation. rate each group subgroup was compared. Results registry search identified 184 fulfilled entry criteria. Logistic regression analysis demonstrated significant predictors presence or absence LHR. 86 cases there (Group A) 98 confined abdomen B). Group A, 50.0% significantly associated LHR; B 76.5% unrelated Conclusion CDH, mortality is substantially higher if liver. herniation, measurement 22–28 useful subsequent survival. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd.