Prenatal prediction of neonatal morbidity in survivors with congenital diaphragmatic hernia: a multicenter study

• DOI: 10.1002/uog.6141
• Publication Date: 2008-12-23T16:02:40Z
• Authors: J. C. Jani; A. Benachi; K. H. Nicolaides; K. Allegaert; E. Gratacós; R. Mazkereth; J. Matis; D. Tibboel; A. Van Heijst; L. Storme; V. Rousseau; A. Greenough; J. A. Deprest
• Keywords: Counseling; Male; Pregnancy Trimester, Third; NCMLS 3: Tissue engineering and pathology; 610; Gestational Age; Ultrasonography, Prenatal; IGMD 1: Functional imaging; 618; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Humans; Lung; Hernia, Diaphragmatic; Infant, Newborn; Feeding Behavior; Prognosis; 3. Good health; Liver; Female; Hernias, Diaphragmatic, Congenital; Lung Volume Measurements; EMC MGC-02-53-01-A; Head

Abstract Objectives To investigate the value of observed to expected fetal lung area head circumference ratio (o/e LHR) and liver position in prediction neonatal morbidity survivors with congenital diaphragmatic hernia (CDH). Methods Neonatal was recorded 100 consecutive cases isolated CDH diagnosed medicine units, which were expectantly managed prenatal period, delivered after 30 weeks survived until discharge from hospital. Regression analysis used identify significant predictors morbidity, including immediate findings. Results The o/e LHR provided need for prosthetic patch repair, duration assisted ventilation, supplemental oxygen at 28 days, incidence feeding problems. An additional independent predictor repair presence chest. Conclusions In prenatally assessed size contralateral is a functional consequences impaired development occurrence Copyright © 2008 ISUOG. Published by John Wiley & Sons, Ltd.