Two‐ and three‐dimensional saline contrast sonohysterography: interobserver agreement, agreement with hysteroscopy and diagnosis of endometrial malignancy

• DOI: 10.1002/uog.6350
• Publication Date: 2009-04-09T11:27:03Z
• Authors: G. Opolskiene; P. Sladkevicius; L. Valentin
• Keywords: Curettage; Contrast-enhanced ultrasound

Abstract Objectives The aims of our study were to compare the interobserver reproducibility two‐dimensional (2D) and three‐dimensional (3D) saline contrast sonohysterography (SCSH) agreement these techniques with hysteroscopy, determine which SCSH findings best discriminate between benign malignant endometrium. Methods Consecutive women postmenopausal bleeding endometrial thickness ≥ 4.5 mm underwent 2D 3D SCSH; results videotaped stored electronically, respectively, for analysis by two independent experienced examiners who blinded each other's results. A histological diagnosis was obtained dilatation curettage, hysteroscopic resection or hysterectomy. hysteroscopist ultrasound used same standardized research protocol describe uterine cavity as examiners. Results Of 170 consecutive mm, 84 (14 malignancy) fulfilled inclusion criteria. Hysteroscopy in 54 (one SCSH. Interobserver 95% (80/84) vs. 89% (75/84) regard presence focal lesions, 88% (74/84) lesions irregular surface, 67% (54/81) 63% (51/81) number 77% (46/60) 70% (42/60) location lesions. hysteroscopy 94% (51/54) 93% (50/54) 74% (40/54) 76% (41/54) (34/54) 54% (29/54) 66% (29/44) 64% (28/44) finding that discriminated endometrium lesion(s) surface (for SCSH: sensitivity 71%, specificity 97%, positive likelihood ratio 25, negative 0.3; 43%, 15, 0.6). Conclusions does not seem be superior when performed either reproducibility, malignancy. is variable discrimination Copyright © 2009 ISUOG. Published John Wiley & Sons, Ltd.