Mapping from Sound to Meaning: Reduced Lexical Activation in Broca's Aphasics

• DOI: 10.1006/brln.2001.2500
• Publication Date: 2002-09-16T14:51:08Z
• Authors: Jennifer Aydelott...; Sheila E. Blumstein; Kelly Sullivan
• Keywords: Adult; Aged, 80 and over; Male; Aphasia, Broca; Sound Spectrography; 05 social sciences; Brain; Middle Aged; Neuropsychological Tests; Severity of Illness Index; Vocabulary; Semantics; Phonetics; Reaction Time; Speech Discrimination Tests; Speech Perception; Humans; Female; 0501 psychology and cognitive sciences; Aged

Recent studies of lexical access in Broca's aphasics suggest that lexical activation levels are reduced in these patients. The present study compared the performance of Broca's aphasics with that of normal subjects in an auditory semantic priming paradigm. Lexical decision times were measured in response to word targets preceded by an intact semantically related prime word ("cat"-"dog"), by a related prime in which one segment was acoustically altered to produce a poorer phonetic exemplar ("c*at"-"dog"), and by a semantically unrelated prime ("ring"-"dog"). The effects of the locus of the acoustic distortion within the prime word (initial or final position) and the presence of potential lexical competitors ("cat" --> /gaet/versus "coat" --> "goat") were examined. In normal subjects, the acoustic manipulations produce a small, short-lived reduction in semantic facilitation irrespective of the position of the distortion in the prime word or the presence of a voiced lexical competitor. In contrast, Broca's aphasics showed a large and lasting reduction in priming in response to word-initial acoustic distortions, but only a weak effect of word-final distortions on priming. In both phonetic positions, the effect of distortion was greater for prime words with a lexical competitor. These findings are compatible with the claim that Broca's aphasics have reduced lexical activation levels, which may result in a disruption of the bottom-up access of words on the basis of acoustic input as well as increased vulnerability to competition between acoustically similar lexical items.