Computational Vaccine Design for Common Allergens

• DOI: 10.1007/978-1-0716-3239-0_33
• Publication Date: 2023-05-31T21:02:43Z
• Authors: Nandini Ghosh; Gaurab Sircar; Sudipto Saha
• Keywords: Vaccines; Desensitization, Immunologic; Epitopes, B-Lymphocyte; Computational Biology; Epitopes, T-Lymphocyte; Allergens

In this chapter, the steps of designing candidate vaccine molecules for allergen-specific immunotherapy (AIT) using immunoinformatics are described. The most modern approach of AIT deals with carrier-bound B cell epitope and multi-epitope vaccine molecules. The strategy for designing these molecules and the bioinformatics tools and servers used for that are discussed in detail here.