Estimating Continuous 4D Wall Motion of Cerebral Aneurysms from 3D Rotational Angiography

• DOI: 10.1007/978-3-642-04268-3_18
• Publication Date: 2009-10-01T07:42:56Z
• Authors: Chong Zhang; Mathieu De Craene; Maria-Cruz Villa-...; Jose M. Pozo; Bart H. Bijnens; Alejandro F. Frangi
• Keywords: Rotation; Movement; Cardiac-Gated Imaging Techniques; Reproducibility of Results; Intracranial Aneurysm; Sensitivity and Specificity; Cerebral Angiography; Pattern Recognition, Automated; Radiographic Image Enhancement; Imaging, Three-Dimensional; Artificial Intelligence; Subtraction Technique; Humans; Radiographic Image Interpretation, Computer-Assisted; Tomography, X-Ray Computed; Algorithms

This paper presents a technique to recover dynamic 3D vascular morphology from a single 3D rotational X-ray angiography acquisition. The dynamic morphology corresponding to a canonical cardiac cycle is represented via a 4D B-spline based spatiotemporal deformation. Such deformation is estimated by simultaneously matching the forward projections of a sequence of the temporally deformed 3D reference volume to the entire 2D measured projection sequence. A joint use of two acceleration strategies is also proposed: semi-precomputation of forward projections and registration metric computation based on a narrow-band region-of-interest. Digital and physical phantoms of pulsating cerebral aneurysms have been used for evaluation. Accurate estimation has been obtained in recovering sub-voxel pulsation, even from images with substantial intensity inhomogeneity. Results also demonstrate that the acceleration strategies can reduce memory consumption and computational time without degrading the performance.