A study of hybridoma cell growth and antibody production kinetics in continuous culture

• DOI: 10.1007/bf00155462
• Publication Date: 2004-11-06T05:41:59Z
• Authors: K. S. Low; C. Harbour; J. P. Barford
• Keywords: Specific antibody

A detailed study of cell growth and antibody production kinetics in continuous culture found that the specific rate of antibody production reached a maximum saturated profile at a specific growth rate less than the maximum. This observation is novel and of importance in the understanding of the mechanism of antibody production and/or antibody transport.