Reduction of the cerebellar stimulus effect on rat deiters neurons after chemical destruction of the inferior olive

• DOI: 10.1007/bf00238802
• Publication Date: 2004-09-26T14:24:50Z
• Authors: M. Ito; I. Orlov; I. Shimoyama
• Keywords: Neurons; Afferent Pathways; Time Factors; Pyridines; 05 social sciences; Neural Inhibition; Olivary Nucleus; Electric Stimulation; Rats; Purkinje Cells; Cerebellum; Animals; 0501 psychology and cognitive sciences

After the inferior olive of the rats had been destroyed by administration of 3-Acetylpyridine, the inhibitory effect of cerebellar stimulation on Deiters neurons was substantially reduced, indicating impairment in functions of Purkinje cells and/or their axons after deprivation of climbing fiber afferents from the cerebellum.