Detection of a hepatitis B virus variant with a truncated X gene and enhancer II

• DOI: 10.1007/bf01309646
• Publication Date: 2005-03-25T17:30:26Z
• Authors: R. Repp; C. Keller; A. Borkhardt; A. Csecke; S. Schaefer; W. H. Gerlich; F. Lampert
• Keywords: 0301 basic medicine; Hepatitis B virus; Molecular Sequence Data; Hepatitis B; 3. Good health; Hepatitis B Antigens; 03 medical and health sciences; Enhancer Elements, Genetic; Carrier State; DNA, Viral; Trans-Activators; Humans; Viral Regulatory and Accessory Proteins; Amino Acid Sequence; Child

Approximately 15% of the viral genomes in the serum of a hepatitis B carrier were found to exhibit an 8 base-pair deletion within the enhancer II element, which would truncate the X protein by 26 amino acids at the carboxy-terminus.