Dipeptidyl aminopeptidase in neonatal rat brain regions

• DOI: 10.1007/bf01947572
• Publication Date: 2005-07-27T17:14:11Z
• Authors: K. Imai; T. Kato
• Keywords: 0303 health sciences; Brain; Rats, Inbred Strains; Rats; 03 medical and health sciences; Animals, Newborn; Pregnancy; Endopeptidases; Animals; Female; Tissue Distribution; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Subcellular Fractions

Changes in the activity of dipeptidyl aminopeptidase in rat pituitary gland and various brain regions were examined at 3, 5 and 20 weeks of age. The enzyme activity per g tissue wet weight in pituitary gland was the highest of all tissues studied. Subcellular distribution of the activity was also studied. The highest enzyme activity was found in a crude mitochondrial fraction including synaptosomes.