Role of follow-up in management of local recurrences of colorectal cancer

• DOI: 10.1007/bf02239434
• Publication Date: 2005-11-14T17:00:59Z
• Authors: Nicola Pietra; Leopoldo Sarli; Renato Costi; Choua Ouchemi; Mario Grattarola; Anacleto Peracchia
• Keywords: Group B; Group A; Surgical oncology; Colorectal Surgery

PURPOSE: This prospective, randomized, single-center study was designed to evaluate the influence of follow-up on detection and resectability local recurrences survival after radical surgery for colorectal cancer. METHODS: Between 1987 1990, 207 consecutive patients who underwent curative resections primary untreated large-bowel carcinoma were randomly assigned a conventional group (Group A; n=103) an intense B; n=104). All followed up prospectively, outcome known all them at five years. Patients in Group A seen six-month intervals one year, once year thereafter. B checked every three months during first two years, next RESULTS: Of 103 A, recurrence detected 20; 9 (13 percent) these had colon cancer, 11 (29 rectal 104 B, 26; 12 (16 14 (45 Twelve cases (60 24 (92 scheduled visits (P<0.05). Local earlier (10.3±2.7 vs. 20.2±6.1 months; P<0.0003). Curative re-resection possible 2 (10 1 with cancer 17 (65 6 (P<0.01). re-resections recurrence, 8 (47 disease-free long-term survivors as last follow-up, (11.7 alive, but new recurrence. The died result five-year rate 58.3 percent 73.1 percent. difference is statistically significant (P < 0.02). CONCLUSIONS: Our data support use plan resection least