Computer controlled glucoregulation in the diabetic dog

• DOI: 10.1007/bf02409339
• Publication Date: 2006-04-20T00:22:30Z
• Authors: G. Hetenyi; B. Pagurek; G. Fluker; J. Anthony; I. Popescu; K. H. Norwich
• Keywords: Blood Glucose; Dogs; Glucose; Computers; 0206 medical engineering; Diabetes Mellitus; Animals; Insulin; 02 engineering and technology

Based on a model of the experimentally validated glucoregulatory system operating in the normal dog, an automatic control system has been developed that restores and maintains the normal concentration of glucose in blood in nonanesthetized pancreatectomized dogs. The relative success of the experiments largely validates the model of the disturbed glucoregulatory system.