Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses

• DOI: 10.1007/bf02973148
• Publication Date: 2021-12-17T15:44:54Z
• Authors: Xiaodong Zhang; Xiaohong Guo; Guili Xu; Ling Guo; Zhaojiu Zhang; Yuncheng Hou; Zhengxian Zhang; Lanxi Song; Qingyun Zeng; Jiaxiong Jiang

Objective: To observe the therapeutic effect of compound decoction of Comcide (CDC), a traditional Chinese medicine (TCM) in treating the withdrawal reaction (WR) of heroin dependent rhesuses (HDR).Methods: To study therapeutic effects of CDC and methadone in treating WR of HDR models induced by administering of heroin. Through observing, comparing and evaluating the scores of all groups gained during the first 4 days when the WR was most severe.Results: CDC and methadone had the same therapeutic effects on WR of HDR. There were significant differences between the scores of CDC and methadone, and that of natural withdrawal,P 0.05.Conclusion: CDC had the therapeutic effect in treating WR of HDR.