Longitudinal Assessment of Quality of Life in Rectal Cancer Patients With or Without Stomas Following Primary Resection

• DOI: 10.1007/dcr.0b013e31819eb970
• Publication Date: 2011-04-07T17:22:04Z
• Authors: Thomas Yau; David Watkins; David Cunningham; Yolanda Barbachano; Ian Chau; Geoffrey Chong
• Keywords: Surgical oncology; Colorectal Surgery

PURPOSE: The purpose of this study was to assess the longitudinal impact stoma formation on health-related quality life rectal cancer patients treated with adjuvant chemotherapy. METHODS: Health-related data prospectively collected in a randomized trial designed compare 24 weeks bolus 5-fluorouracil/leucovorin 12 continuous 5-fluorouracil resected Dukes B and C colorectal cancer. at baseline, during treatment, one three years after completion RESULTS: Between 1993 2003, 186 were enrolled. One hundred thirty-nine had anterior resection, whom 46 temporary defunctioning colostomy. Forty-seven abdominoperineal resection permanent There no significant difference global between without any time point. However, role (P = 0.04) social 0.005) functioning significantly worse than nonstoma patients. Moreover, impairment persisted 0.03) CONCLUSION: Our results demonstrate important adverse effects either or subsequent