Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation

• DOI: 10.1007/s00062-024-01394-3
• Publication Date: 2024-02-28T14:02:00Z
• Authors: Ying Wang; Bo Chen; Laixin Song; Yuzhe Li; Ming Xu; Tianxiang Huang; Feiyue Zeng
• Keywords: Siphon (mollusc); Saccular aneurysm; Tortuosity; Computed Tomography Angiography

Abstract Purpose Tortuosity of the internal carotid artery (ICA) is associated with intracranial aneurysms (IAs). The siphon most curved segment ICA, but its morphology has controversial effects on IAs. This study aimed to explore morphometric features and potential hemodynamic mechanisms that may affect C7 aneurysm formation. Methods In this 32 patients diagnosed at Xiangya Hospital between 2019 2021 control subjects were enrolled after propensity score matching. Computed tomography angiography (CTA) images acquired measure morphologic features, then, by combining clinical data, simplified models constructed, computational fluid dynamics (CFD) analysis was performed. Results presence height C4–C6 arteries (odds ratio [OR] 0.028, 95% confidence interval [CI] 0.003–0.201; P < 0.001). heights in group significantly shorter than those group. CFD revealed bends led greater blood velocity pressure arteries. Conclusion A bend distal formation, an elaborate mechanism underlie association.