Survival among 148 patients with an incidentally detected appendiceal tumours at surgery for acute appendicitis: a population-based cohort follow-up study

• DOI: 10.1007/s00068-024-02580-1
• Publication Date: 2024-07-17T19:02:01Z
• Authors: Lennart Boström; Viktor Jovic; Martin Dahlberg; Fredrik Holtenius; Gabriel Sandblom; Hans Järnbert-Pet...
• Keywords: Sports medicine; Surgical oncology

Abstract Purpose To investigate the long-term prognosis of appendiceal tumours incidentally detected at appendicectomy for suspicion benign appendicitis. Methods A retrospective register-based single centre cohort study was carried out, using data from local acute quality register cases operated on Department Surgery, South General Hospital, Stockholm, Sweden. The colorectal cancer also used to identify appendix tumours. period between January 2004 and 2023. Survival calculated according Kaplan-Meier method. Results total 11,888 patients were registered in register, 54% males 46% females, median age 32 (Q1 = 21, Q3 47) (with 33.7% 41 years or older). From registers 148 (1.2% cohort) found; 60% females 40% males, 56 43, 70) 78.4% being Tumours found were: Low grade Appendiceal Mucinous Neoplasms (LAMN, N 64); Neuroendocrine (NET 24); adenocarcinomas other form carcinomas ( 57); adenomas 3). overall 5-year survival LAMN 96.8%, NET 93.3% adenocarcinoma 69.7%. all tumour 85.7%. For younger (< 51 years) with NET, almost survived end follow-up. carcinoma group statistically significantly lower than groups, especially older. In undergoing surgery n 146), primary laparoscopic 47% open 52%. Two did not undergo due widespread disease. 64% operation acute, whereas it delayed and/or planned 34%. Most procedures 36%, followed by 30%, right-sided hemicolectomy 14.6% (open 11.6% 3%, 5.5%), ileocaecal resection 5% (acute 3.4%), staging laparoscopy 7%. 38% discovered histopathology examination. had CRS HIPEC as initial operation. Forthy-three per cent 146 underwent a second procedure: 23.3% 13.6% (laparoscopic 8.2% 5.4%). Conclusion high but so carcinoma. older 50 years, those sick females.