Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study

Adult Male Adolescent Endocrinology, Diabetes and Metabolism Short Communication Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Glucose Intolerance Internal Medicine Diabetes Mellitus Prevalence Humans Sex Distribution Aged Glucose Metabolism Disorders Aged, 80 and over Age Factors Middle Aged Health Surveys 3. Good health Cross-Sectional Studies Spain Female
DOI: 10.1007/s00125-011-2336-9 Publication Date: 2011-10-10T19:01:23Z
ABSTRACT
The Di@bet.es Study is the first national study in Spain to examine the prevalence of diabetes and impaired glucose regulation.A population-based, cross-sectional, cluster sampling study was carried out, with target population being the entire Spanish population. Five thousand and seventy-two participants in 100 clusters (health centres or the equivalent in each region) were randomly selected with a probability proportional to population size. Participation rate was 55.8%. Study variables were a clinical and demographic structured survey, lifestyle survey, physical examination (weight, height, BMI, waist and hip circumference, blood pressure) and OGTT (75 g).Almost 30% of the study population had some carbohydrate disturbance. The overall prevalence of diabetes mellitus adjusted for age and sex was 13.8% (95% CI 12.8, 14.7%), of which about half had unknown diabetes: 6.0% (95% CI 5.4, 6.7%). The age- and sex-adjusted prevalence rates of isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT) and combined IFG-IGT were 3.4% (95% CI 2.9, 4.0%), 9.2% (95% CI 8.2, 10.2%) and 2.2% (95% CI 1.7, 2.7%), respectively. The prevalence of diabetes and impaired glucose regulation increased significantly with age (p < 0.0001), and was higher in men than in women (p < 0.001).The Di@bet.es Study shows, for the first time, the prevalence rates of diabetes and impaired glucose regulation in a representative sample of the Spanish population.
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