Arterial pressure changes during the Valsalva maneuver to predict fluid responsiveness in spontaneously breathing patients

• DOI: 10.1007/s00134-008-1295-1
• Publication Date: 2008-10-01T03:50:32Z
• Authors: Manuel Ignacio Mo...; Anselmo Gil Cano; Juan Carlos Díaz ...
• Keywords: Male; Critical Care; Valsalva Maneuver; Hypovolemia; Plasma Substitutes; Blood Pressure; Stroke Volume; Middle Aged; Hydroxyethyl Starch Derivatives; Intensive Care Units; 03 medical and health sciences; 0302 clinical medicine; ROC Curve; Predictive Value of Tests; Poster Presentation; Humans; Female; Aged

To evaluate whether arterial pressure response during a Valsalva maneuver could predict fluid responsiveness in spontaneously breathing patients.Prospective clinical study in a 17-bed multidisciplinary intensive care unit.Thirty patients without mechanical ventilation and equipped with a radial arterial catheter for whom the decision to give fluids was taken due to suspected hypovolemia.A 10-s Valsalva maneuver was performed before and after volume expansion (VE). Patients were classified as responders if stroke volume index (SVi) increased >/=15% after VE.Pulse pressure changes during the Valsalva maneuver (VPP) were calculated as the difference between maximal pulse pressure during phase 1 and minimal pulse pressure during phase 2 of the Valsalva maneuver divided by the mean of the two values and expressed as a percentage. Valsalva changes in systolic pressure (VSP) were calculated in similar way. SVi changes induced by VE was correlated with baseline values of VPP and VSP (r (2) = 0.71 and r (2) = 0.60; P < 0.0001, respectively), and with VE-induced changes in VPP and VSP (r (2) = 0.56 and r (2) = 0.44; P < 0.0001 and P < 0.001, respectively). A VPP value of 52% and VSP of 30% predicted fluid responsiveness with a sensitivity of 91% and 73% and a specificity of 95 and 90%, respectively.Arterial response during the Valsalva maneuver is a feasible tool for predicting fluid responsiveness in patients without mechanical ventilatory support.