Hypovitaminosis D as a risk factor of hip fracture severity

• DOI: 10.1007/s00198-011-1588-z
• Publication Date: 2011-03-10T11:33:01Z
• Authors: M. Larrosa; A. Gomez; E. Casado; M. Moreno; I. Vázquez; C. Orellana; E. Berlanga; J. Ramon; J. Gratacos
• Keywords: Aged, 80 and over; Male; Trauma Severity Indices; Hip Fractures; Nutritional Status; Vitamin D Deficiency; Femoral Neck Fractures; 3. Good health; 03 medical and health sciences; Cross-Sectional Studies; 0302 clinical medicine; Risk Factors; Activities of Daily Living; Dietary Supplements; Humans; Female; Vitamin D; Osteoporotic Fractures; Aged; Calcifediol

In a cross-sectional study including 324 patients older than 65 years admitted to our hospital for osteoporotic hip fracture, we found that those patients with a more severe vitamin D deficiency had more severe osteoporotic hip fractures (Garden grades III-IV and Kyle III-IV).To identify possible differences in baseline characteristics of patients with different types of osteoporotic hip fracture.Cross-sectional study including consecutive individuals over 65 admitted to our hospital for osteoporotic hip fracture over a year. Demographic data, fracture type, comorbidities, history of osteoporosis, functional capacity, nutritional status and vitamin D storage were evaluated.We included 324 patients (83 ± 7 years, 80% women). Two hundred sixteen patients (67%) had vitamin D deficiency (25OHD3 <25 ng/ml). In patients with severe femoral neck or intertrochanteric fractures (Garden III-IV and Kyle III-IV), vitamin D deficiency was more frequent (74%) and severe (25OHD3 20 ± 15 ng/ml) than in patients with less severe fractures (57%, 25OHD3 26 ± 21 ng/ml). Forty-three percent of patients had previous fractures. Only 15% of patients had been previously diagnosed with osteoporosis and 10% were receiving treatment. Patients receiving vitamin D supplements have higher 20OHD3 levels and less severe fractures.Although vitamin D levels are not different between patients with intracapsular or extracapsular hip fractures, a more severe vitamin D deficiency seems to be associated to more severe osteoporotic hip fractures. A prior vitamin D supplementation could avoid a higher severity of these fractures.