The role of varenicline on alcohol-primed self-administration and seeking behavior in rats

• DOI: 10.1007/s00213-015-3878-1
• Publication Date: 2015-02-06T02:03:15Z
• Authors: Patrick A. Randall; Anel A. Jaramillo; Suzanne Frisbee; Joyce Besheer
• Keywords: Varenicline; Self-administration

Varenicline, a smoking-cessation agent, may be useful in treating alcohol use disorders. An important consideration when studying factors that influence drinking/relapse is influence of the pharmacological effects of alcohol on these behaviors. Pre-exposure to alcohol (priming) can increase craving, drinking and seeking behaviors.