Impact of Resistance Training on Bone During 40% Caloric Restriction in Growing Female Rats

• DOI: 10.1007/s00223-025-01348-y
• Publication Date: 2025-02-10T12:01:40Z
• Authors: Ken D. Sumida; Daniel L. Smithers; Aaron Gerston; Kim A. Lagerborg; S. Victoria Jaque; Fred Caporaso
• Keywords: Dual energy; Caloric theory; Bone Health; Bone mineral content

There is a growing trend in the use of severe caloric restrictive diets among normal weight young females that can jeopardize bone health. Using an animal model, purpose this study was to determine whether resistance training (RT) could maintain health during 6-week (CR) diet female rats. Twenty-four rats (~ 8 weeks old) were randomly divided into following groups: sedentary fed (N = 8), 40% CR (D and RT group (DT 8). The DT climbed vertical ladder four consecutive times (per exercise session) with weights appended their tail 3 days/week for total 6 weeks. Tibial mineral density (BMD) assessed using dual-energy X-ray absorptiometry scans mechanical properties measured. After weeks, body mass (Mean ± SD) CR-fed groups & 202.8 10.7 g) significantly lower than N (275.5 25.3 g). BMD (g/cm2) D (0.196 0.012) vs. (0.213 0.013), resulting 7.9% decline. tibial (0.206 0.009) resulted 3.3% decline compared not different. Bone greater D, but different N. Resistance has potential restriction