Conventional magnetic resonance imaging key features for distinguishing pathologically confirmed corticobasal degeneration from its mimics: a retrospective analysis of the J-VAC study

• DOI: 10.1007/s00234-024-03432-w
• Publication Date: 2024-07-22T20:18:26Z
• Authors: Keita Sakurai; Aya M. Tokumaru; Mari Yoshida; Yuko Saito; Koichi Wakabayashi; Takashi Komori; Masato Hasegawa; Takeshi Ikeuchi; Yuichi Hayashi; Takayoshi Shimohata; Shigeo Murayama; Yasushi Iwasaki; Toshiki Uchihara; Motoko Sakai; Ichiro Yabe; Satoshi Tanikawa; Hiroshi Takigawa; Tadashi Adachi; Ritsuko Hanajima; Harutoshi Fujimura; Kentaro Hayashi; Keizo Sugaya; Kazuko Hasegawa; Terunori Sano; Masaki Takao; Osamu Yokota; Tomoko Miki; Michio Kobayashi; Nobutaka Arai; Takuya Ohkubo; Takanori Yokota; Keiko Mori; Masumi Ito; Chiho Ishida; Jiro Idezuka; Yasuko Toyoshima; Masato Kanazawa; Masashi Aoki; Takafumi Hasegawa; Hirohisa Watanabe; Atsushi Hashizume; Hisayoshi Niwa; Keizo Yasui; Keita Ito; Yukihiko Washimi; Akatsuki Kubota; Tatsushi Toda; Kenji Nakashima; Ikuko Aiba
• Keywords: Corticobasal degeneration; Frontotemporal lobar degeneration; Semantic dementia; Neuroradiology

Due to the indistinguishable clinical features of corticobasal syndrome (CBS), antemortem differentiation between degeneration (CBD) and its mimics remains challenging. However, utility conventional magnetic resonance imaging (MRI) for diagnosis CBD has not been sufficiently evaluated. This study aimed investigate diagnostic performance MRI findings in differentiating pathologically confirmed from mimics.